Sepiwhite™ MSH is an excellent skin lightener and brightener suitable for all skin types and ethnicities that promotes a more uniform and radiant complexion with results in as little as seven days. Studies have demonstrated an increase in skin luminosity and decrease in the number and color of hyperpigmented spots, and it can be combined with other active ingredients, such as niacinamide or AHAs. Sepiwhite™ MSH is a lipoamino acid or vectorized essential amino acid developed from phenylalanine, an amino acid involved in melanin synthesis. MSH is an alpha-melanocyte-stimulating hormone (MSH) receptor agonist developed from this amino acid that inhibits the process of melanin synthesis from the hypothalamus to produce a reduction in melanin pigments in skin cells.

In two studies, 1% Sepiwhite™ MSH was combined with 5% niacinamide in lotion. Volunteers reported a reduction in hyperpigmentation after 8 weeks of usage.
In an eight week study using 2% Sepiwhite™ MSH alone, 83% of volunteers reported a more radiant complexion, 73% fewer age spots, 100% lighter age spots, and 100% more even complexion and skin tone.

In a seven day study using Sepiwhite™ MSH alone, volunteers reported hyperpigmentation was reduced by 24% and skin luminosity increased by 9%
Sepiwhite™ MSH. can be combined with a number of other ingredients designed to assist with hyperpigmentation. It can be combined with AHAs to promote a more radiant complexion and more even skin tone.

In studies using 0.2% Sepiwhite™ MSH and 2% ascorbyl glucoside, it doubled the lightning action resulting in a 13% decrease in melanin pigments.
In a two month study using Sepiwhite™ MSH alone, skin’s luminosity was increased by +1.13 L*, a measure of skin’s brightness.

Key Benefits
Promotes a more uniform and more radiant complexion
Promotes reduction of number and color of age spots
Demonstrated effectiveness for all skin types and ethnicities
Promotes a more even skin tone
Reported visible increases in skin luminosity and brightness

ECOcert
Preservative free, paraben free phthalate free
Readily biodegradable
Non-phototoxic

Applications
Anti-aging products for face and body, including gels, emulsions, and toners
Daily skin rejuvenating products, like sera, targeted treatments, and moisturizers
Revitalizing products such as toners, gels, masks, and eye products
Skin lightening make-up removers
Pressed and loose mineral makeup powders, including foundations and highlighters
Find this used in commercial products like these:
Miracle Worker Dark Spot Corrector - Philosophy
TimeWise Even Complexion Essence - Mary Kay
Brightening Night Restore - Janssen Cosmetics
Renewed Radiance Dark Spot Eraser - Nuance Salma Hayek

INCI: Undecylenoyl phenylalanine  

Disclaimer 
Statements contained herein have not been evaluated by the Health Canada and Food and Drug Administration. These products are not intended to diagnose, treat and cure or prevent disease. Always consult with your professional skin care provider.

Use 0.2% in combination with another brightener, otherwise up to 2% in the heated water or heated oil phase of a formulation at more than 60°C (140°F).

In a product with pH 5 or lower, incorporate into any type of formula.

In a product above pH 5, but below 6.2, can incorporate with the use of up to 20% ethanol. Not the ideal pH range for this ingredient.

In a product with pH 6.2 or higher, incorporation into any type of formula is possible.

Tags: Sepiwhite